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KBeauty Verified™ — K-beauty checked against official records from Korea, the EU and the U.S.

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Alphaprodine Hydrochloride; 4-Piperidinol, 1,3-dimethyl-4-phenyl-, propanoate (ester), hydrochloride, cis-(+-)-

Korean: 알파프로딘하이드로클로라이드;4-피페리디놀,1,3-다이메틸-4-페닐-프로파노에이트(에스터),하이드로클로라이드,cis-(+-)- · CAS 561-78-4 ·

KR South Korea (MFDS)

Prohibited MFDS prohibited ingredients

Conditions (official MFDS text, Korean):
다만, 같은 법 제2조제4호 단서에 따른 대마씨유 및 대마씨추출물의 테트라하이드로칸나비놀 및 칸나비디올에 대하여는 「식품의 기준 및 규격」에서 정한 기준에 적합한 경우는 제외

Source: MFDS — cosmetic ingredient use restrictions · checked Oct 17, 2026

EU European Union (CosIng)

No specific rule on file.

US United States (FDA)

No specific rule on file. The FDA regulates few cosmetic ingredients by name; no rule does not mean approval.

Other markets

How Alphaprodine Hydrochloride; 4-Piperidinol, 1,3-dimethyl-4-phenyl-, propanoate (ester), hydrochloride, cis-(+-)- is treated in 5 more markets, from the overseas cosmetic regulation database compiled by Korea's MFDS. Always confirm with the regulator of that country before selling there.

Market	Status	Conditions
CN China	Prohibited	—
AS ASEAN (10 countries)	Prohibited	—
CA Canada	Prohibited	—
BR Brazil	Prohibited	—
AR Argentina	Prohibited	—

Source: MFDS cosmetic ingredient use restrictions — overseas regulations · checked Oct 17, 2026

Also listed as

Alphaprodine Hydrochloride; 4-Piperidinol, 1,3-dimethyl-4-phenyl-, propanoate (ester), hydrochloride, cis-(+-)- 알파프로딘하이드로클로라이드;4-피페리디놀,1,3-다이메틸-4-페닐-프로파노에이트(에스터),하이드로클로라이드,cis-(+-)-

Information only, not medical advice. Rules change — always check the linked official source. If you are pregnant, have a skin condition or allergies, ask a dermatologist or pharmacist.

Frequently asked questions

Is Alphaprodine Hydrochloride; 4-Piperidinol, 1,3-dimethyl-4-phenyl-, propanoate (ester), hydrochloride, cis-(+-)- banned in the European Union?

We found no specific rule for it in the EU's CosIng records. That is not an approval or a safety statement.

Is Alphaprodine Hydrochloride; 4-Piperidinol, 1,3-dimethyl-4-phenyl-, propanoate (ester), hydrochloride, cis-(+-)- banned in South Korea?

In Korea's MFDS records it is listed as “Prohibited” (MFDS — cosmetic ingredient use restrictions).

Is Alphaprodine Hydrochloride; 4-Piperidinol, 1,3-dimethyl-4-phenyl-, propanoate (ester), hydrochloride, cis-(+-)- allowed in cosmetics in the U.S.?

We found no specific rule for it in the FDA's records. That is not an approval or a safety statement.

What is Alphaprodine Hydrochloride; 4-Piperidinol, 1,3-dimethyl-4-phenyl-, propanoate (ester), hydrochloride, cis-(+-)- called on Korean labels?

Korea's MFDS standard Korean name is 알파프로딘하이드로클로라이드;4-피페리디놀,1,3-다이메틸-4-페닐-프로파노에이트(에스터),하이드로클로라이드,cis-(+-)-.

What is the CAS number of Alphaprodine Hydrochloride; 4-Piperidinol, 1,3-dimethyl-4-phenyl-, propanoate (ester), hydrochloride, cis-(+-)-?

CAS 561-78-4 (from official records).