Korean: 등색201호 · Functions: colorant
Restricted MFDS restricted ingredients
Conditions (official MFDS text, Korean):
* 배합한도 : 눈 주위에 사용할 수 없음
Source: MFDS — cosmetic ingredient use restrictions · checked Oct 16, 2026
Prohibited only in certain forms or uses Annex II/1333
Conditions: 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one; 4',5'-Dibromofluorescein; (Solvent Red 72) and its disodium salt (CI 45370) when used as a substance in hair dye products
Source: EU CosIng — Annex II · checked Oct 17, 2026
Approved colorant Annex IV/75
Conditions: 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its insoluble barium, strontium and zirconium lakes, salts and pigments
Required label warning: Not more than 1% 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid and 2% 2-(bromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid
Source: EU CosIng — Annex IV · checked Oct 17, 2026
No specific rule on file. The FDA regulates few cosmetic ingredients by name; no rule does not mean approval.
How CI 45370 is treated in 5 more markets, from the overseas cosmetic regulation database compiled by Korea's MFDS. Always confirm with the regulator of that country before selling there.
| Market | Status | Conditions |
|---|---|---|
| CN China | Restricted | MFDS summary (Korean): * 기타 제한조건 및 요구사항 : 2-(6-히드록시-3-옥소-3H-크산텐-9-yl)벤조산이 1% 를 초과하지 않음, 2-(Bromo-6-히드록시-3-옥소-3H-크산텐-9-yl)벤조산이 2%를 초과하지 않음. 염색제품에 사용금지 * 착색제 【사용허가 범위】 : 각종 화장품 |
| AS ASEAN (10 countries) | Restricted | MFDS summary (Korean): when used as a substance in hair dye products^염모제로 사용되는 경우에 한함 (2) The insoluble barium, strontium and zirconium lakes, salts and pigments of these colouring agents shall also be permitted. They must pass the test for insolubility which will be determined by the procedure laid down in Article... |
| TW Taiwan | Restricted | MFDS summary (Korean): 1. 所列色素與非禁用成分形成之麗基（lakes）及鹽（salts）亦可使用。 2. 未列載於此表規定範圍之成分，於歐盟、美國及日本三國家地區，任何其中一個國家地區官方已公告（以生效日為準）其使用基準者，得參照其基準規定准予使用(但下表CI 11380 等十九項成分不適用)，惟於申請查驗登記時，應同時檢附該等地區之准許使用基準證明文件。 * 단서조항 : 1. 所列色素與非禁用成分形成之麗基（lakes）及鹽（salts）亦可使用。 2.... |
| BR Brazil | Restricted | MFDS summary (Korean): * Restrictions 【Field of application and/or use】 : Dye Substances allowed for all kinds of products. * 제한 【사용 범위】 : 모든 종류의 제품에서 허용된 염색 성분 * Restrictions 【Other limitations and requirements】 : <cortado> No more than 1% Hydroxi-3-oxo-3H-Benzoic (fluoresceAcid 2-(bromo-6-Xantin-9-yl) benzoic... |
| AR Argentina | Restricted | MFDS summary (Korean): * Restrictions 【Field of application and/or use】 : Dye Substances allowed for all kinds of products. * 제한 【사용 범위】 : 모든 종류의 제품에서 허용된 염색 성분 * Restrictions 【Other limitations and requirements】 : <cortado> No more than 1% Hydroxi-3-oxo-3H-Benzoic (fluoresceAcid 2-(bromo-6-Xantin-9-yl) benzoic... |
Source: MFDS cosmetic ingredient use restrictions — overseas regulations · checked Oct 17, 2026
CI 45370 D&C Orange 5 D&C Orange No. 5 D&C Orange No.5
Information only, not medical advice. Rules change — always check the linked official source. If you are pregnant, have a skin condition or allergies, ask a dermatologist or pharmacist.
In the EU's CosIng records it is listed as “Prohibited only in certain forms or uses” (EU CosIng — Annex II). The same records also list it as: Approved colorant. It is not a general ban — the condition reads: “4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one; 4',5'-Dibromofluorescein; (Solvent Red 72) and its disodium salt (CI 45370) when used as a substance in hair dye products”
In Korea's MFDS records it is listed as “Restricted” (MFDS — cosmetic ingredient use restrictions). A restricted ingredient is allowed within the stated conditions.
We found no specific rule for it in the FDA's records. That is not an approval or a safety statement.
The EU's CosIng inventory lists its functions as: colorant.
Korea's MFDS standard Korean name is 등색201호.