Korean: N,N-비스(2-히드록시에틸)-p-페닐렌디아민설페이트 · CAS 54381-16-7 ,57524-61-5 ,58262-44-5 ·
No specific rule on file.
Restricted Annex III/8
Maximum: (a) General use (b) Professional use For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 3 % calculated as free base
Conditions: Product type: Hair dye substance in oxidative hair dye products (1 ) These substances may be used singly or in combination provided that the sum of the ratios of the levels of each of them in the cosmetic product expressed with reference to the maximum level authorised for each of them does not exceed 1.’
Required label warning: (a) To be printed on the label: The mixing ratio. “ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past. Contains phenylenediamines. Do not use to dye eyelashes or eyebrows” (b) To be printed on the label: The mixing ratio. “For professional use only Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past. Contains phenylenediamines. Wear suitable gloves”
Source: EU CosIng — Annex III · checked Oct 17, 2026
No specific rule on file. The FDA regulates few cosmetic ingredients by name; no rule does not mean approval.
N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE
Information only, not medical advice. Rules change — always check the linked official source. If you are pregnant, have a skin condition or allergies, ask a dermatologist or pharmacist.
In the EU's CosIng records it is listed as “Restricted” (EU CosIng — Annex III). The maximum allowed is (a) General use (b) Professional use For (a) and (b): After mixing under…. A restricted ingredient is allowed within the stated conditions.
We found no specific rule for it in Korea's MFDS records. That is not an approval or a safety statement.
We found no specific rule for it in the FDA's records. That is not an approval or a safety statement.
Korea's MFDS standard Korean name is N,N-비스(2-히드록시에틸)-p-페닐렌디아민설페이트.
CAS 54381-16-7 ,57524-61-5 ,58262-44-5 (from official records).