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KBeauty Verified™ — K-beauty checked against official records from Korea, the EU and the U.S.

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N,N'-Pentamethylenebis(trimethylammonium) salts, e.g. pentamethonium bromide (INN)

Korean: N,N'-펜타메틸렌비스(트라이메틸암모늄)염류 (예 : 펜타메토늄브로마이드) · CAS 541-20-8 ·

KR South Korea (MFDS)

Prohibited MFDS prohibited ingredients

Source: MFDS — cosmetic ingredient use restrictions · checked Oct 17, 2026

EU European Union (CosIng)

Prohibited Annex II/120

Source: EU CosIng — Annex II · checked Oct 17, 2026

US United States (FDA)

No specific rule on file. The FDA regulates few cosmetic ingredients by name; no rule does not mean approval.

Other markets

How N,N'-Pentamethylenebis(trimethylammonium) salts, e.g. pentamethonium bromide (INN) is treated in 6 more markets, from the overseas cosmetic regulation database compiled by Korea's MFDS. Always confirm with the regulator of that country before selling there.

Market	Status	Conditions
CN China	Prohibited	—
AS ASEAN (10 countries)	Prohibited	—
TW Taiwan	Prohibited	—
CA Canada	Prohibited	—
BR Brazil	Prohibited	—
AR Argentina	Prohibited	—

Source: MFDS cosmetic ingredient use restrictions — overseas regulations · checked Oct 17, 2026

Also listed as

N,N'-Pentamethylenebis(trimethylammonium) salts, e.g. pentamethonium bromide (INN) N,N'-펜타메틸렌비스(트라이메틸암모늄)염류 (예 : 펜타메토늄브로마이드)

Information only, not medical advice. Rules change — always check the linked official source. If you are pregnant, have a skin condition or allergies, ask a dermatologist or pharmacist.

Frequently asked questions

Is N,N'-Pentamethylenebis(trimethylammonium) salts, e.g. pentamethonium bromide (INN) banned in the European Union?

In the EU's CosIng records it is listed as “Prohibited” (EU CosIng — Annex II).

Is N,N'-Pentamethylenebis(trimethylammonium) salts, e.g. pentamethonium bromide (INN) banned in South Korea?

In Korea's MFDS records it is listed as “Prohibited” (MFDS — cosmetic ingredient use restrictions).

Is N,N'-Pentamethylenebis(trimethylammonium) salts, e.g. pentamethonium bromide (INN) allowed in cosmetics in the U.S.?

We found no specific rule for it in the FDA's records. That is not an approval or a safety statement.

What is N,N'-Pentamethylenebis(trimethylammonium) salts, e.g. pentamethonium bromide (INN) called on Korean labels?

Korea's MFDS standard Korean name is N,N'-펜타메틸렌비스(트라이메틸암모늄)염류 (예 : 펜타메토늄브로마이드).

What is the CAS number of N,N'-Pentamethylenebis(trimethylammonium) salts, e.g. pentamethonium bromide (INN)?

CAS 541-20-8 (from official records).